Regression of coronary artery disease with lipid-lowering therapy

Background: The prevalence of CAD has progressively increased in India during latter half the last century particularly among urban population. present study assessed regression coronary artery disease as a result intensive lipid-lowering therapy men.Materials and Methods: 60 males with elevated apolipoprotein B level were classified according to triglyceride level: 73 less than 2.3 mmol per liter [200 mg deciliter], 59 more liter) into 3 groups. Group I was treatment niacin colestipol, group II lovastatin III conventional therapy. Patients received Colestipol 10 g three times day after days 500 four for one month. In II, 20 Lovastatin twice given above III, patients placebos colestipol lovastatin, described above.Results: Age 20-40 years had 8 I, 9 40-60 12 11 III. mean percentage change stenosis 2.0, -0.8 -0.9. difference significant (P< 0.05).Conclusion: who at high risk cardiovascular events, reduced frequency progression lesions, regression, incidence events.